مشخصات کلی Is salivary chromogranin A a valid psychological stress biomarker during sensory stimulation in people with advanced dementia?

نویسنده کتاب (Author):

Valdiglesias, Vanessa; Maseda, Ana; Lorenzo-López, Laura; Pásaro, Eduardo; Millán-Calenti, José Carlos; Laffon, Blanca

انتشارات (Publisher):

IOS Press 2016-12-20

ویرایش و نوع فایل (Edition/Format):

 Downloadable article : English

منبع (Database):

WorldCat

عنوان ژورنال (Publication):

valdiglesias-v-maseda-a-lorenzo-lopez-l-pasaro-e-millan-calenti-jc-laffon-b-is-salivary-chromogranin-a-a-valid-psychological-stress-biomarker-during-sensory-stimulation-in-peop

موضوع (Subject):

Chromogranin A       Dementia       Individualized music       View all subjects      

توضیحات خلاصه (Summary):

[Abstract] Salivary chromogranin A (sCgA) is gaining attention as a biomarker of psychological stress. The objective of this work was to determine whether individualized music intervention and multisensory stimulation environment (MSSE) in a Snoezelen room produce changes in sCgA in severely demented older patients, and to assess the possible existence of differences in sCgA levels between the two types of interventions. Older adults with severe dementia (n = 22) were randomly assigned to two intervention groups. They participated in MSSE or individualized music interventions in 30-min weekly sessions for 16 weeks. Levels of sCgA were evaluated before and after a session, or 30-min interval, at four different time points: before starting the trial, in the middle and end of the intervention period, and two months later. Comparison of sCgA values obtained after each session with those obtained before (or at the same hour in before trial and follow-up samplings) showed no significant differences either in the individualized music or in the MSSE group at any sampling time. Comparison between the two types of interventions, both before and after each session, in the four sampling times, did not produce any significant difference either. Furthermore, no significant correlation was obtained between agitation, anxiety, cognitive function, and dementia severity with sCgA levels. In conclusion, despite beneficial effects of both individualized music and MSSE interventions being previously reported on neuropsychiatric outcomes for older patients with dementia, sCgA seems to not be a good indicator of these benefits.  Read more…

ژانر / فرم:info:eu-repo/semantics/article

موضوع:Internet resource

نوع منبع:Internet Resource, Article

تمام نویسندگان / همکاران: Valdiglesias, Vanessa; Maseda, Ana; Lorenzo-López, Laura; Pásaro, Eduardo; Millán-Calenti, José Carlos; Laffon, Blanca

شناسه OCLC:979265416

Language Note:English

فهرست محتوا:1387-2877 1875-8908 http://hdl.handle.net/2183/17988

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